Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), represents a global crisis. Key to SARS-CoV-2 therapeutic development is unraveling the mechanisms that drive high infectivity, broad tissue tropism, and severe pathology. Our 2.85-angstrom c...

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Pubblicato in:Science
Autori principali: Toelzer, Christine, Gupta, Kapil, Yadav, Sathish K. N., Borucu, Ufuk, Davidson, Andrew D., Kavanagh Williamson, Maia, Shoemark, Deborah K., Garzoni, Frederic, Staufer, Oskar, Milligan, Rachel, Capin, Julien, Mulholland, Adrian J., Spatz, Joachim, Fitzgerald, Daniel, Berger, Imre, Schaffitzel, Christiane
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050947/
https://ncbi.nlm.nih.gov/pubmed/32958580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abd3255
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