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Kv1.5 channels are regulated by PKC-mediated endocytic degradation

The voltage-gated potassium channel Kv1.5 plays important roles in the repolarization of atrial action potentials and regulation of the vascular tone. While the modulation of Kv1.5 function has been well studied, less is known about how the protein levels of Kv1.5 on the cell membrane are regulated....

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Du, Yuan, Wang, Tingzhong, Guo, Jun, Li, Wentao, Yang, Tonghua, Szendrey, Mark, Zhang, Shetuan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050386/
https://ncbi.nlm.nih.gov/pubmed/33676894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100514
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