Kv1.5 channels are regulated by PKC-mediated endocytic degradation

The voltage-gated potassium channel Kv1.5 plays important roles in the repolarization of atrial action potentials and regulation of the vascular tone. While the modulation of Kv1.5 function has been well studied, less is known about how the protein levels of Kv1.5 on the cell membrane are regulated....

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Vydáno v:J Biol Chem
Hlavní autoři: Du, Yuan, Wang, Tingzhong, Guo, Jun, Li, Wentao, Yang, Tonghua, Szendrey, Mark, Zhang, Shetuan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050386/
https://ncbi.nlm.nih.gov/pubmed/33676894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100514
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