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An in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients
The tumor microenvironment (TME) is multi-cellular, spatially heterogenous, and contains cell-generated gradients of soluble molecules. Current cell-based model systems lack this complexity or are difficult to interrogate microscopically. We present a 2D live-cell chamber that approximates the TME a...
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| Publicado no: | Commun Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8050328/ https://ncbi.nlm.nih.gov/pubmed/33859337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01954-0 |
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