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Environmental exposures and the etiopathogenesis of Alzheimer’s disease: the potential role of BACE1 as a critical neurotoxic target
Alzheimer’s disease (AD) is a major public health crisis due to devastating cognitive symptoms, a lack of curative treatments, and increasing prevalence. Most cases are sporadic (>95% of cases) after the age of 65 years, implicating an important role of environmental factors in disease pathogenes...
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| Veröffentlicht in: | J Biochem Mol Toxicol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8049945/ https://ncbi.nlm.nih.gov/pubmed/33393683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbt.22694 |
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