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Environmental exposures and the etiopathogenesis of Alzheimer’s disease: the potential role of BACE1 as a critical neurotoxic target

Alzheimer’s disease (AD) is a major public health crisis due to devastating cognitive symptoms, a lack of curative treatments, and increasing prevalence. Most cases are sporadic (>95% of cases) after the age of 65 years, implicating an important role of environmental factors in disease pathogenes...

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Detalhes bibliográficos
Publicado no:J Biochem Mol Toxicol
Main Authors: Syeda, Tauqeerunnisa, Cannon, Jason R
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049945/
https://ncbi.nlm.nih.gov/pubmed/33393683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbt.22694
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