MAFG-driven astrocytes promote CNS inflammation

Multiple sclerosis is a chronic inflammatory disease of the CNS(1). Astrocytes contribute to the pathogenesis of multiple sclerosis(2), but little is known about the heterogeneity of astrocytes and its regulation. Here we report the analysis of astrocytes in multiple sclerosis and its preclinical mo...

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Vydáno v:Nature
Hlavní autoři: Wheeler, Michael A., Clark, Iain C., Tjon, Emily C., Li, Zhaorong, Zandee, Stephanie E. J., Couturier, Charles P., Watson, Brianna R., Scalisi, Giulia, Alkwai, Sarah, Rothhammer, Veit, Rotem, Assaf, Heyman, John A., Thaploo, Shravan, Sanmarco, Liliana M., Ragoussis, Jiannis, Weitz, David A., Petrecca, Kevin, Moffitt, Jeffrey R., Becher, Burkhard, Antel, Jack P., Prat, Alexandre, Quintana, Francisco J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049843/
https://ncbi.nlm.nih.gov/pubmed/32051591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-1999-0
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