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Lymphocyte Infiltration Determines the Hypoxia-Dependent Response to Definitive Chemoradiation in Head-and-Neck Cancer: Results from a Prospective Imaging Trial

Tumor hypoxia in head-and-neck squamous cell carcinoma (HNSCC) leads to an immunosuppressive microenvironment and reduces the response to radiotherapy. In this prospective imaging trial, we investigated potential interactions between functional hypoxia imaging and infiltrating lymphocyte levels as a...

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Bibliografiske detaljer
Udgivet i:J Nucl Med
Main Authors: Nicolay, Nils H., Rühle, Alexander, Wiedenmann, Nicole, Niedermann, Gabriele, Mix, Michael, Weber, Wolfgang A., Baltas, Dimos, Werner, Martin, Kayser, Gian, Grosu, Anca-L.
Format: Artigo
Sprog:Inglês
Udgivet: Society of Nuclear Medicine 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049369/
https://ncbi.nlm.nih.gov/pubmed/32859699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.120.248633
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