Lymphocyte Infiltration Determines the Hypoxia-Dependent Response to Definitive Chemoradiation in Head-and-Neck Cancer: Results from a Prospective Imaging Trial

Tumor hypoxia in head-and-neck squamous cell carcinoma (HNSCC) leads to an immunosuppressive microenvironment and reduces the response to radiotherapy. In this prospective imaging trial, we investigated potential interactions between functional hypoxia imaging and infiltrating lymphocyte levels as a...

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Detalhes bibliográficos
Publicado no:J Nucl Med
Main Authors: Nicolay, Nils H., Rühle, Alexander, Wiedenmann, Nicole, Niedermann, Gabriele, Mix, Michael, Weber, Wolfgang A., Baltas, Dimos, Werner, Martin, Kayser, Gian, Grosu, Anca-L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Nuclear Medicine 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049369/
https://ncbi.nlm.nih.gov/pubmed/32859699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.120.248633
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