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Longitudinal Molecular Imaging of Progesterone Receptor Reveals Early Differential Response to Endocrine Therapy in Breast Cancer with an Activating ESR1 Mutation

Activating mutations in the estrogen receptor (ER) α-gene (ESR1) result in constitutive transcriptional activity in the absence of estrogen and are associated with endocrine resistance in metastatic ER-positive (+) breast cancer. It is not known how activating ESR1 mutations may alter the predictive...

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Bibliografiske detaljer
Udgivet i:J Nucl Med
Main Authors: Kumar, Manoj, Salem, Kelley, Jeffery, Justin J., Yan, Yongjun, Mahajan, Aparna M., Fowler, Amy M.
Format: Artigo
Sprog:Inglês
Udgivet: Society of Nuclear Medicine 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049365/
https://ncbi.nlm.nih.gov/pubmed/32859700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.120.249508
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