First-in-Human Evaluation of (18)F-SynVesT-1, a Radioligand for PET Imaging of Synaptic Vesicle Glycoprotein 2A

The use of synaptic vesicle glycoprotein 2A radiotracers with PET imaging could provide a way to measure synaptic density quantitatively in living humans. (11)C-UCB-J ((R)-1-((3-((11)C-methyl-(11)C)pyridin-4-yl)methyl)-4-(3,4,5-trifluorophenyl)pyrrolidin-2-one), previously developed and assessed in...

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Detalhes bibliográficos
Publicado no:J Nucl Med
Main Authors: Naganawa, Mika, Li, Songye, Nabulsi, Nabeel, Henry, Shannan, Zheng, Ming-Qiang, Pracitto, Richard, Cai, Zhengxin, Gao, Hong, Kapinos, Michael, Labaree, David, Matuskey, David, Huang, Yiyun, Carson, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Nuclear Medicine 2021
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049363/
https://ncbi.nlm.nih.gov/pubmed/32859701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.120.249144
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