Use of amplicon-based sequencing for testing fetal identity and monogenic traits with Single Circulating Trophoblast (SCT) as one form of cell-based NIPT

A major challenge for cell-based non-invasive prenatal testing (NIPT) is to distinguish individual presumptive fetal cells from maternal cells in female pregnancies. We have sought a rapid, robust, versatile, and low-cost next-generation sequencing method to facilitate this process. Toward this goal...

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Udgivet i:PLoS One
Main Authors: Zhuo, Xinming, Wang, Qun, Vossaert, Liesbeth, Salman, Roseen, Kim, Adriel, Van den Veyver, Ignatia, Breman, Amy, Beaudet, Arthur
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049273/
https://ncbi.nlm.nih.gov/pubmed/33857205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0249695
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