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Phosphorylation of the mRNA cap-binding protein eIF4E and cancer

Dysregulated protein synthesis is frequently involved in oncogenesis and cancer progression. Translation initiation is thought to be the rate-limiting step in protein synthesis, and the mRNA 5’ cap-binding protein eukaryotic translation initiation factor 4E (eIF4E) is a pivotal factor that initiates...

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Bibliographic Details
Published in:Cell Signal
Main Authors: Yang, Xiaotong, Zhong, Wu, Cao, Ruifeng
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049097/
https://ncbi.nlm.nih.gov/pubmed/32535199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2020.109689
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