Pharmacokinetics and Optimal Dose Selection of Cefazolin for Surgical Prophylaxis of Pediatric Patients

Cefazolin is an antibiotic frequently used for perioperative prophylaxis. Data from healthy adults and pediatric surgery patients were pooled to refine a previously developed population pharmacokinetic (PK) model and to determine the optimal body weight cutoff for selecting fixed doses of either 1 o...

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Detalhes bibliográficos
Publicado no:J Clin Pharmacol
Main Authors: Schmitz, Michael L., Rubino, Christopher M., Onufrak, Nikolas J., Martinez, Diana Valencia, Licursi, Diane, Karpf, Angela, Cetnarowski, Wes
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Pediatric Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049034/
https://ncbi.nlm.nih.gov/pubmed/33202066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1785
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