Pharmacokinetics and Optimal Dose Selection of Cefazolin for Surgical Prophylaxis of Pediatric Patients

Cefazolin is an antibiotic frequently used for perioperative prophylaxis. Data from healthy adults and pediatric surgery patients were pooled to refine a previously developed population pharmacokinetic (PK) model and to determine the optimal body weight cutoff for selecting fixed doses of either 1 o...

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Bibliografiske detaljer
Udgivet i:J Clin Pharmacol
Main Authors: Schmitz, Michael L., Rubino, Christopher M., Onufrak, Nikolas J., Martinez, Diana Valencia, Licursi, Diane, Karpf, Angela, Cetnarowski, Wes
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Pediatric Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049034/
https://ncbi.nlm.nih.gov/pubmed/33202066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1785
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