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Pharmacokinetic and Pharmacodynamic Target Attainment in Adult and Pediatric Patients Following Administration of Ceftaroline Fosamil as a 5‐Minute Infusion

The key pharmacokinetic/pharmacodynamic (PK/PD) efficacy index for β‐lactam antibiotics is the percentage of time that free drug concentrations exceed the minimum inhibitory concentration (MIC) of bacteria during each dosing interval (fT>MIC). Ceftaroline fosamil, the prodrug of the β‐lactam ceft...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Drug Dev
Main Authors: Riccobene, Todd A., Carrothers, Timothy J., Knebel, William, Raber, Susan, Chan, Phylinda L.S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048922/
https://ncbi.nlm.nih.gov/pubmed/33465279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.907
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