Platelet Glycoprotein Ib α‐Chain as a Putative Therapeutic Target for Juvenile Idiopathic Arthritis: A Mendelian Randomization Study

OBJECTIVE: To ascertain the role of platelet glycoprotein Ib α‐chain (GPIbα) plasma protein levels in cardiovascular, autoimmune, and autoinflammatory diseases and whether its effects are mediated by platelet count. METHODS: We performed a two‐sample Mendelian randomization (MR) study, using both a...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Luo, Shan, Clarke, Sarah L. N., Ramanan, Athimalaipet V., Thompson, Susan D., Langefeld, Carl D., Marion, Miranda C., Grom, Alexei A., Schooling, C. Mary, Gaunt, Tom R., Yeung, Shiu Lun Au, Zheng, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Pediatric Rheumatology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048917/
https://ncbi.nlm.nih.gov/pubmed/33079445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41561
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