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Physiologically‐Based Pharmacokinetic Modeling Combined with Swiss HIV Cohort Study Data Supports No Dose Adjustment of Bictegravir in Elderly Individuals Living With HIV

Clinical studies in aging people living with HIV (PLWH) are sparse for the novel integrase inhibitor bictegravir, leading to some uncertainty about dosing recommendations for elderly PLWH. The objective of this study was to investigate the continuous impact of aging on bictegravir pharmacokinetics b...

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Bibliografiska uppgifter
I publikationen:Clin Pharmacol Ther
Huvudupphovsmän: Stader, Felix, Courlet, Perrine, Decosterd, Laurent A., Battegay, Manuel, Marzolini, Catia
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048864/
https://ncbi.nlm.nih.gov/pubmed/33521960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.2178
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