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A Randomized, Double‐Blind, Placebo‐ and Positive‐Controlled, 4‐Period Crossover Study of the Effects of Solriamfetol on QTcF Intervals in Healthy Participants

Solriamfetol, a dopamine and norepinephrine reuptake inhibitor, is approved (United States and European Union; Sunosi) to treat excessive daytime sleepiness associated with narcolepsy (75‐150 mg/day) or obstructive sleep apnea (37.5‐150 mg/day). A thorough QT/QTc study assessed solriamfetol effects...

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Bibliografische gegevens
Gepubliceerd in:Clin Pharmacol Drug Dev
Hoofdauteurs: Zomorodi, Katie, Chen, Dan, Lee, Lawrence, Swearingen, Dennis, Carter, Lawrence P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048583/
https://ncbi.nlm.nih.gov/pubmed/32935460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.867
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