Efficacy and safety of chronomodulated irinotecan, oxaliplatin, 5‐fluorouracil and leucovorin combination as first‐ or second‐line treatment against metastatic colorectal cancer: Results from the International EORTC 05011 Trial

The triplet combination of irinotecan, oxaliplatin and fluorouracil is an active frontline regimen in metastatic colorectal cancer, but scarce data exist on its use as salvage treatment. We aimed at assessing its safety and efficacy profiles with its circadian‐based administration (chronoIFLO5) as e...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Int J Cancer
Autori principali: Innominato, Pasquale F., Karaboué, Abdoulaye, Focan, Christian, Chollet, Philippe, Giacchetti, Sylvie, Bouchahda, Mohamed, Ulusakarya, Ayhan, Torsello, Angela, Adam, René, Lévi, Francis A., Garufi, Carlo
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2020
Soggetti:
Cancer Therapy and Prevention
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048520/
https://ncbi.nlm.nih.gov/pubmed/33270911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.33422
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