Efficacy and safety of chronomodulated irinotecan, oxaliplatin, 5‐fluorouracil and leucovorin combination as first‐ or second‐line treatment against metastatic colorectal cancer: Results from the International EORTC 05011 Trial

The triplet combination of irinotecan, oxaliplatin and fluorouracil is an active frontline regimen in metastatic colorectal cancer, but scarce data exist on its use as salvage treatment. We aimed at assessing its safety and efficacy profiles with its circadian‐based administration (chronoIFLO5) as e...

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Detalles Bibliográficos
Publicado en:Int J Cancer
Main Authors: Innominato, Pasquale F., Karaboué, Abdoulaye, Focan, Christian, Chollet, Philippe, Giacchetti, Sylvie, Bouchahda, Mohamed, Ulusakarya, Ayhan, Torsello, Angela, Adam, René, Lévi, Francis A., Garufi, Carlo
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Inc. 2020
Assuntos:
Cancer Therapy and Prevention
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048520/
https://ncbi.nlm.nih.gov/pubmed/33270911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.33422
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