TNFα secreted by glioma associated macrophages promotes endothelial activation and resistance against anti-angiogenic therapy

One of the most prominent features of glioblastoma (GBM) is hyper-vascularization. Bone marrow-derived macrophages are actively recruited to the tumor and referred to as glioma-associated macrophages (GAMs) which are thought to provide a critical role in tumor neo-vascularization. However, the mecha...

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Veröffentlicht in:Acta Neuropathol Commun
Hauptverfasser: Wei, Qingxia, Singh, Olivia, Ekinci, Can, Gill, Jaspreet, Li, Mira, Mamatjan, Yasin, Karimi, Shirin, Bunda, Severa, Mansouri, Sheila, Aldape, Kenneth, Zadeh, Gelareh
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048292/
https://ncbi.nlm.nih.gov/pubmed/33853689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01163-0
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