TAMI-46. TNFα SECRETED BY GLIOMA ASSOCIATED MACROPHAGES PROMOTES ENDOTHELIAL ACTIVATION AND RESISTANCE AGAINST ANTI-ANGIOGENIC THERAPY

Glioblastoma (GBM) remains a universal fatal disease and improving survival remains a challenge. One of the most prominent features of GBM is hyper-vascularization, characterized by abnormally dilated, distorted, and leaky vessels. Bone marrow (BM)-derived macrophages are recognized to be an importa...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Wei, Qingxia, Singh, Olivia, Ekinci, Can, Gill, Jaspreet, Li, Mira, Yasin, Mamatjan, Karimi, Shirin, Bunda, Severa, Mansouri, Sheila, Aldape, Kenneth, Zadeh, Gelareh
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Tumor Microenvironment/Angiogenesis/Metabolism/Invasion
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651642/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.933
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