Glutathione S-Transferase P Influences Redox Homeostasis and Response to Drugs that Induce the Unfolded Protein Response in Zebrafish

We have created a novel glutathione S-transferase π1 (gstp1) knockout (KO) zebrafish model and used it for comparative analyses of redox homeostasis and response to drugs that cause endoplasmic reticulum (ER) stress and induce the unfolded protein response (UPR). Under basal conditions, gstp1 KO lar...

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Bibliografiset tiedot
Julkaisussa:J Pharmacol Exp Ther
Päätekijät: Zhang, Leilei, Kim, Seok-Hyung, Park, Ki-Hoon, Townsend, Danyelle M., Tew, Kenneth D., Zhi-wei, Ye, Jie, Zhang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Pharmacology and Experimental Therapeutics 2021
Aiheet:
Cellular and Molecular
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047768/
https://ncbi.nlm.nih.gov/pubmed/33514607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.120.000417
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