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Upregulation of antioxidant and autophagy pathways via NRF2 activation protects spinal cord neurons from ozone damage

Ozone therapy can relieve multiple types of pain but exhibits potential neurotoxicity, the mechanism of which is unclear. The present study aimed to identify the role of nuclear factor (erythroid-derived-2)-related 2 (NRF2) in preventing spinal cord injury caused by ozone overdose. Primary neuronal...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Med Rep
Main Authors: Zhang, Cong, Ma, Shulin, Zhao, Xu, Wen, Bei, Sun, Panpan, Fu, Zhijian
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047762/
https://ncbi.nlm.nih.gov/pubmed/33846774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.12067
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