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Upregulation of antioxidant and autophagy pathways via NRF2 activation protects spinal cord neurons from ozone damage

Ozone therapy can relieve multiple types of pain but exhibits potential neurotoxicity, the mechanism of which is unclear. The present study aimed to identify the role of nuclear factor (erythroid-derived-2)-related 2 (NRF2) in preventing spinal cord injury caused by ozone overdose. Primary neuronal...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Zhang, Cong, Ma, Shulin, Zhao, Xu, Wen, Bei, Sun, Panpan, Fu, Zhijian
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047762/
https://ncbi.nlm.nih.gov/pubmed/33846774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.12067
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