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Upregulation of antioxidant and autophagy pathways via NRF2 activation protects spinal cord neurons from ozone damage

Ozone therapy can relieve multiple types of pain but exhibits potential neurotoxicity, the mechanism of which is unclear. The present study aimed to identify the role of nuclear factor (erythroid-derived-2)-related 2 (NRF2) in preventing spinal cord injury caused by ozone overdose. Primary neuronal...

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Dettagli Bibliografici
Pubblicato in:Mol Med Rep
Autori principali: Zhang, Cong, Ma, Shulin, Zhao, Xu, Wen, Bei, Sun, Panpan, Fu, Zhijian
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047762/
https://ncbi.nlm.nih.gov/pubmed/33846774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.12067
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