Smyd1 Orchestrates Early Heart Development Through Positive and Negative Gene Regulation

SET and MYND domain-containing protein 1 (Smyd1) is a striated muscle-specific histone methyltransferase. Our previous work demonstrated that deletion of Smyd1 in either cardiomyocytes or the outflow tract (OFT) resulted in embryonic lethality at E9.5, with cardiac structural defects such as truncat...

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Publicat a:Front Cell Dev Biol
Autors principals: Wang, Zhen, Schwartz, Robert J., Liu, Jing, Sun, Fei, Li, Qi, Ma, Yanlin
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047137/
https://ncbi.nlm.nih.gov/pubmed/33869215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.654682
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