Smyd1 Orchestrates Early Heart Development Through Positive and Negative Gene Regulation

SET and MYND domain-containing protein 1 (Smyd1) is a striated muscle-specific histone methyltransferase. Our previous work demonstrated that deletion of Smyd1 in either cardiomyocytes or the outflow tract (OFT) resulted in embryonic lethality at E9.5, with cardiac structural defects such as truncat...

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Publicado en:Front Cell Dev Biol
Autores principales: Wang, Zhen, Schwartz, Robert J., Liu, Jing, Sun, Fei, Li, Qi, Ma, Yanlin
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047137/
https://ncbi.nlm.nih.gov/pubmed/33869215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.654682
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