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Smyd1 Orchestrates Early Heart Development Through Positive and Negative Gene Regulation

SET and MYND domain-containing protein 1 (Smyd1) is a striated muscle-specific histone methyltransferase. Our previous work demonstrated that deletion of Smyd1 in either cardiomyocytes or the outflow tract (OFT) resulted in embryonic lethality at E9.5, with cardiac structural defects such as truncat...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Wang, Zhen, Schwartz, Robert J., Liu, Jing, Sun, Fei, Li, Qi, Ma, Yanlin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047137/
https://ncbi.nlm.nih.gov/pubmed/33869215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.654682
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