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Anti-ICOS mAb Targets Pathogenic IL-17A–expressing Cells in Canine Model of Chronic GVHD
BACKGROUND: Chronic graft-versus-host disease (GVHD) is a significant cause of morbidity and mortality in transplant patients. We have previously shown that 3 doses of an anti-ICOS mAb transiently ameliorated symptoms and extended survival of dogs affected by chronic GVHD over that of control dogs....
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| Publicado no: | Transplantation |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8046842/ https://ncbi.nlm.nih.gov/pubmed/33065723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000003489 |
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