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Regulator of G protein signaling 17 represents a novel target for treating cisplatin induced hearing loss

Regulators of G protein signaling (RGS) accelerate the GTPase activity of G proteins to enable rapid termination of the signals triggered by G protein-coupled receptors (GPCRs). Activation of several GPCRs, including cannabinoid receptor 2 (CB2R) and adenosine A(1) receptor (A(1)AR), protects agains...

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Foilsithe in:Sci Rep
Main Authors: Dhukhwa, Asmita, Al Aameri, Raheem F. H., Sheth, Sandeep, Mukherjea, Debashree, Rybak, Leonard, Ramkumar, Vickram
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8046767/
https://ncbi.nlm.nih.gov/pubmed/33854102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87387-5
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