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The AXL-PYK2-PKCα axis as a nexus of stemness circuits in TNBC
Cancer stem cells (CSCs) are implicated in tumor initiation, metastasis and drug resistance, and considered as attractive targets for cancer therapy. Here we identified a clinically relevant signaling nexus mediated by AXL receptor, PYK2 and PKCα and show its impact on stemness in TNBC. AXL, PYK2, a...
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| Publicado no: | Life Sci Alliance |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Life Science Alliance LLC
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8046419/ https://ncbi.nlm.nih.gov/pubmed/33785524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000985 |
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