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Proper CycE–Cdk2 activity in endocycling tissues requires regulation of the cyclin-dependent kinase inhibitor Dacapo by dE2F1b in Drosophila

Polyploidy is an integral part of development and is associated with cellular stress, aging, and pathological conditions. The endocycle, comprised of successive rounds of G and S phases without mitosis, is widely employed to produce polyploid cells in plants and animals. In Drosophila, maintenance o...

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Dettagli Bibliografici
Pubblicato in:Genetics
Autori principali: Kim, Minhee, Delos Santos, Keemo, Moon, Nam-Sung
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045689/
https://ncbi.nlm.nih.gov/pubmed/33683365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/genetics/iyaa029
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