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The cyclin-dependent kinase inhibitor Dacapo promotes replication licensing during Drosophila endocycles

The endocycle is a developmentally programmed variant cell cycle in which cells undergo repeated rounds of DNA replication with no intervening mitosis. In Drosophila, the endocycle is driven by the oscillations of Cyclin E/Cdk2 activity. How the periodicity of Cyclin E/Cdk2 activity is achieved duri...

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Detalhes bibliográficos
Main Authors: Hong, Amy, Narbonne-Reveau, Karine, Riesgo-Escovar, Juan, Fu, Haiqing, Aladjem, Mirit I, Lilly, Mary A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852775/
https://ncbi.nlm.nih.gov/pubmed/17380129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601648
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