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Pseurotin A as a Novel Suppressor of Hormone Dependent Breast Cancer Progression and Recurrence by Inhibiting PCSK9 Secretion and Interaction with LDL Receptor

Hypercholesterolemia has been documented to drive hormone-dependent breast cancer (BC) progression and resistance to hormonal therapy. Proprotein convertase subtilisin/kexin type-9 (PCSK9) regulates cholesterol metabolism through binding to LDL receptor (LDLR) and targeting the receptor for lysosoma...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Pharmacol Res
मुख्य लेखकों: Abdelwahed, Khaldoun S., Siddique, Abu Bakar, Mohyeldin, Mohamed M., Qusa, Mohammed H., Goda, Amira A., Singh, Sitanshu S., Ayoub, Nehad M., King, Judy Ann, Jois, Seetharama D., El Sayed, Khalid A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045554/
https://ncbi.nlm.nih.gov/pubmed/32438039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2020.104847
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