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Targeting novel inhibitory receptors in cancer immunotherapy

T cells play a critical role in promoting tumor regression in both experimental models and humans. Yet, T cells that are chronically exposed to tumor antigen during cancer progression can become dysfunctional/exhausted and fail to induce tumor destruction. Such tumor-induced T cell dysfunction may o...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Semin Immunol
Main Authors: Ding, Quan-Quan, Chauvin, Joe-Marc, Zarour, Hassane M.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045408/
https://ncbi.nlm.nih.gov/pubmed/33288379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2020.101436
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