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Phase I dose-escalation oncology trials with sequential multiple schedules

BACKGROUND: Conventional methods for phase I dose-escalation trials in oncology are based on a single treatment schedule only. More recently, however, multiple schedules are more frequently investigated in the same trial. METHODS: Here, we consider sequential phase I trials, where the trial proceeds...

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Detalhes bibliográficos
Publicado no:BMC Med Res Methodol
Main Authors: Günhan, Burak Kürsad, Weber, Sebastian, Seroutou, Abdelkader, Friede, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045405/
https://ncbi.nlm.nih.gov/pubmed/33853539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-021-01218-9
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