Markers of T Cell Exhaustion and Senescence and Their Relationship to Plasma TGF-β Levels in Treated HIV+ Immune Non-responders

Background: Immune non-responders (INR) are HIV+, ART-controlled (>2 yrs) people who fail to reconstitute their CD4 T cell numbers. Systemic inflammation and markers of T cell senescence and exhaustion are observed in INR. This study aims to investigate T cell senescence and exhaustion and their...

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Publicado no:Front Immunol
Main Authors: Shive, Carey L., Freeman, Michael L., Younes, Souheil-Antoine, Kowal, Corinne M., Canaday, David H., Rodriguez, Benigno, Lederman, Michael M., Anthony, Donald D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044907/
https://ncbi.nlm.nih.gov/pubmed/33868264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.638010
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