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Genomics-Guided Drawing of Molecular and Pathophysiological Components of Malignant Regulatory Signatures Reveals a Pivotal Role in Human Diseases of Stem Cell-Associated Retroviral Sequences and Functionally-Active hESC Enhancers

Repetitive DNA sequences (repeats) colonized two-third of human genome and a majority of repeats comprised of transposable genetic elements (TE). Evolutionary distinct categories of TE represent nucleic acid sequences that are repeatedly copied from and pasted into chromosomes at multiple genomic lo...

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Detalles Bibliográficos
Publicado en:Front Oncol
Autor Principal: Glinsky, Gennadi V.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044830/
https://ncbi.nlm.nih.gov/pubmed/33869024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.638363
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