Matched miRNA and mRNA signatures from an hESC-based in vitro model of pancreatic differentiation reveal novel regulatory interactions

The differentiation of human pluripotent stem cells (hPSCs) to insulin-expressing beta islet-like cells is a promising in vitro model system for studying the molecular signaling pathways underlying beta cell differentiation, as well as a potential source of cells for the treatment of type 1 diabetes...

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Detalhes bibliográficos
Main Authors: Liao, Xiaoyan, Xue, Haipeng, Wang, Yu-Chieh, Nazor, Kristopher L., Guo, Shuren, Trivedi, Neha, Peterson, Suzanne E., Liu, Ying, Loring, Jeanne F., Laurent, Louise C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757328/
https://ncbi.nlm.nih.gov/pubmed/23813959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.123570
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