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Development of LT-HSC-Reconstituted Non-Irradiated NBSGW Mice for the Study of Human Hematopoiesis In Vivo

Humanized immune system (HIS) mouse models are useful tools for the in vivo investigation of human hematopoiesis. However, the majority of HIS models currently in use are biased towards lymphocyte development and fail to support long-term multilineage leucocytes and erythrocytes. Those that achieve...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Adigbli, George, Hua, Peng, Uchiyama, Masateru, Roberts, Irene, Hester, Joanna, Watt, Suzanne M., Issa, Fadi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044770/
https://ncbi.nlm.nih.gov/pubmed/33868276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.642198
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