Localized EMT reprograms glial progenitors to promote spinal cord repair

Anti-regenerative scarring obstructs spinal cord repair in mammals and presents a major hurdle for regenerative medicine. In contrast, adult zebrafish possess specialized glial cells that spontaneously repair spinal cord injuries by forming a pro-regenerative bridge across the severed tissue. To ide...

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Vydáno v:Dev Cell
Hlavní autoři: Klatt Shaw, Dana, Muraleedharan Saraswathy, Vishnu, Zhou, Lili, McAdow, Anthony R., Burris, Brooke, Butka, Emily, Morris, Samantha A., Dietmann, Sabine, Mokalled, Mayssa H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044706/
https://ncbi.nlm.nih.gov/pubmed/33609461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2021.01.017
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