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Computational Drug Repositioning and Experimental Validation of Ivermectin in Treatment of Gastric Cancer

Objective: The aim of the present study was repositioning of ivermectin in treatment of gastric cancer (GC) by computational prediction based on gene expression profiles of human and mouse model of GC and validations with in silico, in vitro and in vivo approaches. Methods: Computational drug reposi...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Rabben, Hanne-Line, Andersen, Gøran Troseth, Ianevski, Aleksandr, Olsen, Magnus Kringstad, Kainov, Denis, Grønbech, Jon Erik, Wang, Timothy Cragin, Chen, Duan, Zhao, Chun-Mei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044519/
https://ncbi.nlm.nih.gov/pubmed/33867984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.625991
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