Microenvironmental Regulation of Macrophage Transcriptomic and Metabolomic Profiles in Pulmonary Hypertension

The recruitment and subsequent polarization of inflammatory monocytes/macrophages in the perivascular regions of pulmonary arteries is a key feature of pulmonary hypertension (PH). However, the mechanisms driving macrophage polarization within the adventitial microenvironment during PH progression r...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Li, Min, Riddle, Suzette, Kumar, Sushil, Poczobutt, Joanna, McKeon, B. Alexandre, Frid, Maria G., Ostaff, Maureen, Reisz, Julie A., Nemkov, Travis, Fini, Mehdi A., Laux, Aya, Hu, Cheng-Jun, El Kasmi, Karim C., D’Alessandro, Angelo, Brown, R. Dale, Zhang, Hui, Stenmark, Kurt R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044406/
https://ncbi.nlm.nih.gov/pubmed/33868271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.640718
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