Improvement of HSV-1 based amplicon vectors for a safe and long-lasting gene therapy in non-replicating cells

A key factor for developing gene therapy strategies for neurological disorders is the availability of suitable vectors. Currently, the most advanced are adeno-associated vectors that, while being safe and ensuring long-lasting transgene expression, have a very limited cargo capacity. In contrast, he...

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Detalles Bibliográficos
Publicado en:Mol Ther Methods Clin Dev
Autores principales: Soukupová, Marie, Zucchini, Silvia, Trempat, Pascal, Ingusci, Selene, Perrier-Biollay, Coline, Barbieri, Mario, Cattaneo, Stefano, Bettegazzi, Barbara, Falzoni, Simonetta, Berthommé, Hervé, Simonato, Michele
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2021
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044385/
https://ncbi.nlm.nih.gov/pubmed/33869657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2021.03.020
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