Silencing Status Epilepticus-Induced BDNF Expression with Herpes Simplex Virus Type-1 Based Amplicon Vectors

Brain-derived neurotrophic factor (BDNF) has been found to produce pro- but also anti-epileptic effects. Thus, its validity as a therapeutic target must be verified using advanced tools designed to block or to enhance its signal. The aim of this study was to develop tools to silence the BDNF signal....

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Falcicchia, Chiara, Trempat, Pascal, Binaschi, Anna, Perrier-Biollay, Coline, Roncon, Paolo, Soukupova, Marie, Berthommé, Hervé, Simonato, Michele
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783051/
https://ncbi.nlm.nih.gov/pubmed/26954758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150995
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