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Implementing and Assessing an Alchemical Method for Calculating Protein–Protein Binding Free Energy

Protein–protein binding is fundamental to most biological processes. It is important to be able to use computation to accurately estimate the change in protein–protein binding free energy due to mutations in order to answer biological questions that would be experimentally challenging, laborious, or...

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Detaylı Bibliyografya
Yayımlandı:J Chem Theory Comput
Asıl Yazarlar: Patel, Dharmeshkumar, Patel, Jagdish Suresh, Ytreberg, F. Marty
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044032/
https://ncbi.nlm.nih.gov/pubmed/33709712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.0c01045
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