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Converting endogenous genes of the malaria mosquito into simple non-autonomous gene drives for population replacement

Gene drives for mosquito population replacement are promising tools for malaria control. However, there is currently no clear pathway for safely testing such tools in endemic countries. The lack of well-characterized promoters for infection-relevant tissues and regulatory hurdles are further obstacl...

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Pubblicato in:eLife
Autori principali: Hoermann, Astrid, Tapanelli, Sofia, Capriotti, Paolo, Del Corsano, Giuseppe, Masters, Ellen KG, Habtewold, Tibebu, Christophides, George K, Windbichler, Nikolai
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043746/
https://ncbi.nlm.nih.gov/pubmed/33845943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58791
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