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Converting endogenous genes of the malaria mosquito into simple non-autonomous gene drives for population replacement

Gene drives for mosquito population replacement are promising tools for malaria control. However, there is currently no clear pathway for safely testing such tools in endemic countries. The lack of well-characterized promoters for infection-relevant tissues and regulatory hurdles are further obstacl...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Hoermann, Astrid, Tapanelli, Sofia, Capriotti, Paolo, Del Corsano, Giuseppe, Masters, Ellen KG, Habtewold, Tibebu, Christophides, George K, Windbichler, Nikolai
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043746/
https://ncbi.nlm.nih.gov/pubmed/33845943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58791
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