Pharmacokinetics and Safety of Zidovudine, Lamivudine, and Lopinavir/Ritonavir in HIV-infected Children With Severe Acute Malnutrition in Sub-Saharan Africa: IMPAACT Protocol P1092

Severe acute malnutrition (SAM) may alter the pharmacokinetics (PK), efficacy, and safety of antiretroviral therapy. The phase IV study, IMPAACT P1092, compared PK, safety, and tolerability of zidovudine (ZDV), lamivudine (3TC), and lopinavir/ritonavir (LPV/r) in children with and without SAM. MATER...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Pediatr Infect Dis J
Main Authors: Owor, Maxensia, Tierney, Camlin, Ziemba, Lauren, Browning, Renee, Moye, John, Graham, Bobbie, Reding, Christina, Costello, Diane, Norman, Jennifer, Wiesner, Lubbe, Hughes, Emma, Whalen, Meghan E., Purdue, Lynette, Mmbaga, Blandina Theophil, Kamthunzi, Portia, Kawalazira, Rachel, Nathoo, Kusum, Bradford, Sarah, Coletti, Anne, Aweeka, Francesca., Musoke, Philippa
Format: Artigo
Jezik:Inglês
Izdano: Lippincott Williams & Wilkins 2021
Teme:
HIV Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043511/
https://ncbi.nlm.nih.gov/pubmed/33464021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/INF.0000000000003055
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