Pharmacokinetics and Safety of Zidovudine, Lamivudine, and Lopinavir/Ritonavir in HIV-infected Children With Severe Acute Malnutrition in Sub-Saharan Africa: IMPAACT Protocol P1092

Severe acute malnutrition (SAM) may alter the pharmacokinetics (PK), efficacy, and safety of antiretroviral therapy. The phase IV study, IMPAACT P1092, compared PK, safety, and tolerability of zidovudine (ZDV), lamivudine (3TC), and lopinavir/ritonavir (LPV/r) in children with and without SAM. MATER...

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Detalhes bibliográficos
Publicado no:Pediatr Infect Dis J
Main Authors: Owor, Maxensia, Tierney, Camlin, Ziemba, Lauren, Browning, Renee, Moye, John, Graham, Bobbie, Reding, Christina, Costello, Diane, Norman, Jennifer, Wiesner, Lubbe, Hughes, Emma, Whalen, Meghan E., Purdue, Lynette, Mmbaga, Blandina Theophil, Kamthunzi, Portia, Kawalazira, Rachel, Nathoo, Kusum, Bradford, Sarah, Coletti, Anne, Aweeka, Francesca., Musoke, Philippa
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2021
Assuntos:
HIV Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043511/
https://ncbi.nlm.nih.gov/pubmed/33464021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/INF.0000000000003055
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