Structural basis for broad sarbecovirus neutralization by a human monoclonal antibody

The recent emergence of SARS-CoV-2 variants of concern (VOC) and the recurrent spillovers of coronaviruses in the human population highlight the need for broadly neutralizing antibodies that are not affected by the ongoing antigenic drift and that can prevent or treat future zoonotic infections. Her...

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Bibliografske podrobnosti
izdano v:bioRxiv
Main Authors: Tortorici, M. Alejandra, Czudnochowski, Nadine, Starr, Tyler N., Marzi, Roberta, Walls, Alexandra C., Zatta, Fabrizia, Bowen, John E., Jaconi, Stefano, di iulio, Julia, Wang, Zhaoqian, De Marco, Anna, Zepeda, Samantha K., Pinto, Dora, Liu, Zhuoming, Beltramello, Martina, Bartha, Istvan, Housley, Michael P., Lempp, Florian A., Rosen, Laura E., Dellota, Exequiel, Kaiser, Hannah, Montiel-Ruiz, Martin, Zhou, Jiayi, Addetia, Amin, Guarino, Barbara, Culap, Katja, Sprugasci, Nicole, Saliba, Christian, Vetti, Eneida, Giacchetto-Sasselli, Isabella, Silacci Fregni, Chiara, Abdelnabi, Rana, Caroline Foo, Shi-Yan, Havenar-Daughton, Colin, Schmid, Michael A., Benigni, Fabio, Cameroni, Elisabetta, Neyts, Johan, Telenti, Amalio, Snell, Gyorgy, Virgin, Herbert W., Whelan, Sean P.J., Bloom, Jesse D., Corti, Davide, Veesler, David, Pizzuto, Matteo Samuele
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory 2021
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043460/
https://ncbi.nlm.nih.gov/pubmed/33851169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.04.07.438818
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